Jaclyn Brennan


I am a Postdoctoral Scientist in the Efimov Laboratory. My dissertation research focused on dynamically detecting, qualifying, and controlling pacemaker regions of the heart. Specifically, I investigated the acute and chronic effects of beta-adrenergic stimulation in regulating sinoatrial nodal activity. I am also developing novel approaches for cellular reprogramming using tissue engineering and optogenetics.


  • B.S. Materials Science and Engineering, Virginia Tech (2010)
  • M.S. Bioengineering, University of Oklahoma (2012)
  • Ph.D. Biomedical Engineering, The George Washington University (2019)
Contact Information


Science and Engineering Hall, Suite 5000

800 22nd Street, NW

Washington, DC 20052

Recent Publications
  • F.S. Ng, J. Brennan, I. Efimov. “Chapter 35: Optical mapping of arrhythmogenic remodeling in the failing human heart.” Cardiac Mapping 5th Edition – Ed. Mohammad Shenasa, Ed. Gerhard Hindricks, Ed. Martin Borggrefe. John Wiley & Sons, Ltd. 2016. Print.   
  • C. Gloschat, A. Koppel, K. Aras, J. Brennan, K. Holzem, I. Efimov. “Arrhythmogenic and Metabolic Remodeling of Failing Human Heart.” Journal of Physiology, Jun 2016.   
  • C. Kang, J. Brennan, S. Kuzmiak-Glancy, K. Garrott, M. Kay, I. Efimov. “Technical advances in studying cardiac electrophysiology – role of rabbit models.” Progress in Biophysics & Molecular Biology, May 2016.   
  • J. Brennan, J. Arrizabalaga, M. Nollert. “Development of a Small Diameter Vascular Graft Using the Human Amniotic Membrane.” Cardiovascular Engineering and Technology (2013), DOI: 10.1007/s13239-013-0170-6.