Anastasia Carr


I am currently an undergraduate student majoring in biomedical engineering and minoring in electrical engineering here at GW. I started work in the lab in September of 2017, learning how to collect and optically map human organotypic cardiac slices. In the spring of 2018, I was awarded the Clare Boothe Luce Research Fellowship, allowing me to take on my current project under the supervision of Dr.Efimov and Dr.Faye. Now, my work primarily deals with examining the knockdown of two cardiac potassium channels in the human organotypic tissue slice model, which has relevance to both LQTS1 and LQTS2. Using optical mapping, immunolabeling of structural proteins, and molecular analyses of intracellular components, we aim to characterize the effects of silencing repolarizing channels at the human tissue level.